DNA test - Macular corneal dystrophy (MCD)

The DNA test for macular corneal dystrophy (MCD) can be used by breeders and owners to screen their dogs for the gene variant linked to this health condition.

What is macular corneal dystrophy?

MCD is an inherited eye disease that causes problems with a dog’s sight. In affected dogs, a build-up of carbohydrate causes the surface of the eye (the cornea) to become cloudy.

Symptoms of macular corneal dystrophy

Dogs with MCD usually show signs around four to six years old. Affected dogs will have cloudy eyes that may have grey or white spots on the surface. As their eyes become cloudier, they may have problems seeing and may be more likely to bump into things, walk more slowly or may be more nervous when visiting new places. 

What causes macular corneal dystrophy?

Macular corneal dystrophy is an inherited condition, which means that some dogs may be more at risk of a health issue because of the genes they inherited from their parents. This particular disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from their mother and one from their father) before their health is affected.

Which laboratories test for this condition?

Two lists of laboratories that test for macular corneal dystrophy can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
Laboratories Contact details
Canine Genetic Testing (University of Cambridge UK) Email: Canine Genetic Testing
Telephone: 01223 765 860
Website www.cagt.co.uk
Laboklin (UK) Phone: 0161 282 3066
Email: Laboklin Veterinary Diagnostic Laboratory
Web: www.laboklin.co.uk

Where will your dog's results be published?

DNA test results from these laboratories are sent directly to us and are recorded on to the dog's record in the registration database, and are published:

Laboratories that do not send a copy of your dog's results to The Kennel Club. You'll need to do this yourself.
Laboratories Contact details
Embark (USA) Email: Embark Vet
Web: www.embarkvet.com
Paw Print Genetics (USA) Email: Paw Print Genetics
Web: www.pawprintgenetics.com
VetGen (USA) Web: www.vetgen.com

How to submit DNA test results to The Kennel Club

The laboratories listed above do not send your dog's DNA test results to The Kennel Club. To have these results placed on your dog's record please submit them yourself by scanning and emailing them to our health results team.

What we require on the results certificate

Please note that we require at least two forms of identification on the result certificate. These must include the dog's microchip or tattoo number along with either the dog's registered name or registered number. Results without these details cannot be accepted by us.

Where will your dog's results be published once you have submitted them?

DNA test results received by The Kennel Club are added to the dog's record in the registration database, and are published:

Breeding advice and what your dog's results mean

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The health test results finder allows you to find the results of DNA tests carried out as part of our official DNA testing schemes for any dog on The Kennel Club’s Breed Register.