DNA test - LEMP (Leukoencephalomyelopathy)

Details about the disease

LEMP is a neurological disorder that affects the white matter of the central nervous system. The condition usually appears when dogs are young (around one to four years old).

Clinical signs

Slowly worsening problems walking, not walking in a straight line, spontaneous knuckling, dragging of the paws. Dogs may become increasingly immobile over a few months.

How is it inherited?

This disease is described as an autosomal-recessive condition with incomplete penetrance. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. With partial penetrance, some dogs may have two copies of the mutation, but may never develop the condition.

LEMP affects the Leonberger and although it is very similar to LEMP2 (found in Rottweilers), it is inherited in a slightly different way.

Which laboratories test for this condition?

Two lists of laboratories that test for LEMP can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
Laboratories Contact details
Animal DNA Diagnostics (UK) Phone: 01223 395577
Animal DNA Diagnostics
Web: www.animaldnadiagnostics.co.uk
Laboklin (UK) Phone: 0161 282 3066
Email: Laboklin Veterinary Diagnostic Laboratory
Web: www.laboklin.co.uk

Where will your dog's results be published?

DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:

Laboratories that do not send a copy of your dog's results to The Kennel Club. You'll need to do this yourself.
Laboratories Contact details
University of Bern (Switzerland)
Only available for the Leonberger
Web: www.unibe.ch/eng
University of Minnesota (USA)
Only available for the Leonberger
Email: University of Minnesota
Web: www.vdl.umn.edu/services-fees

How to submit DNA test results to The Kennel Club

The laboratories listed above do not send your dog's DNA test results to The Kennel Club. To have these results placed on your dog's record please submit them yourself by scanning and emailing them to our health results team.

What we require on the results certificate

Please note that we require at least two forms of identification on the result certificate. These must include the dog's microchip or tattoo number along with either the dog's registered name or registered number. Results without these details cannot be accepted by us.

Where will your dog's results be published once you have submitted them?

DNA test results received by The Kennel Club are recorded on to the dog's record in the registration database, and are published:

Breeding advice and what your dog's results mean

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.