Details about the disease
JLPP is a disease that causes deterioration of the nervous system. The longest nerve which controls the muscles of the larynx (voice box) is affected first. This leads to muscle weakness and obstruction of air flow into the lungs after exercise or when the dog is hot.
Clinical signs
Clinical signs include noisy breathing, choking and regurgitation of food and water. Signs also include a wobbly gait due to affected nerves that control the hind leg muscles. Other signs include eye development abnormalities. Clinical signs usually start at a few weeks of age.
How is it inherited?
The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.
Which laboratories test for this condition?
A list of laboratories that test for JLPP can be found below.
Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
| Laboratories | Contact details |
|---|---|
| Animal DNA Diagnostics (UK) | Phone: 01223 395577 Email: Animal DNA Diagnostics Web: www.animaldnadiagnostics.co.uk |
| Laboklin (UK) | Phone: 0161 282 3066 Email: Laboklin Web: www.laboklin.co.uk |
| Pet Genetics Lab (UK) | Phone: 01624 679 720 Email: Pet Genetics Lab Web: www.petgeneticslab.co.uk |
Where will your dog's results be published?
DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:
- in the next available Breed Records Supplement
- on our Health Test Results Finder
How to responsibly breed from your DNA-tested dog
If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.
How to find out if a potential mate has been DNA tested
The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.