DNA test – DP-LHX3 (pituitary dwarfism)

Details about the disease

Pituitary dwarfism is a genetic condition caused by a growth hormone deficiency. This hormone is produced by the pituitary gland, hence the name ‘pituitary dwarfism’. Affected puppies may not be noticeably different at birth, but will not grow correctly and can die young.

Clinical signs

Affected dogs will be smaller than other dogs of the same breed and may remain puppy like in their appearance. Typically dogs with pituitary dwarfism retain their soft puppy coat, may develop hair loss or have problems with tooth development.

How is it inherited?

This disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected.

Which laboratories test for this condition?

A list of laboratories that test for pituitary dwarfism can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
Laboratories Contact details
Animal DNA Diagnostics (UK) Phone: 01223 395577
Animal DNA Diagnostics
Web: www.animaldnadiagnostics.co.uk
Laboklin (UK) Phone: 0161 282 3066
Email: Laboklin Veterinary Diagnostic Laboratory
Web: www.laboklin.co.uk

Where will your dog's results be published?

DNA test results from these laboratories are sent directly to us and are recorded on to the dog's record in the registration database, and are published:

Breeding advice and what your dog's results mean

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The health test results finder allows you to find the results of DNA tests carried out as part of our official DNA testing schemes for any dog on The Kennel Club’s Breed Register.