DNA test – DP-LHX3 (pituitary dwarfism)

Details about the disease

Pituitary dwarfism is a genetic condition caused by a growth hormone deficiency. This hormone is produced by the pituitary gland, hence the name ‘pituitary dwarfism’. Affected puppies may not be noticeably different at birth, but will not grow correctly and can die young.

Clinical signs

Affected dogs will be smaller than other dogs of the same breed and may remain puppy like in their appearance. Typically dogs with pituitary dwarfism retain their soft puppy coat, may develop hair loss or have problems with tooth development.

How is it inherited?

This disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected.

Which laboratories we record and publish the results from?

To find out which laboratories The Kennel Club is able to record results from, and which laboratories will send results directly to The Kennel Club, please refer to our website.

Please be aware, The Kennel Club has a set of criteria that we request DNA testing laboratories to meet to enable us to record their results, helping to maintain and protect the integrity of results that appear on a dog’s record. We strongly advise that customers ensure their chosen laboratory is included on our list if they wish The Kennel Club to record and publish the results. Results from laboratories not included on this list will not be recorded.

Breeding advice and what your dog's results mean

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The health test results finder allows you to find the results of DNA tests carried out as part of our official DNA testing schemes for any dog on The Kennel Club’s Breed Register.