DNA test - BBS2 - PRA (Progressive retinal atrophy)

Details about the disease

PRA (Progressive Retinal Atrophy) is a condition that causes the parts of the eye that are sensitive to light to break down. PRA produces a gradual loss of vision in both eyes, eventually leading to total blindness. A number of breeds are affected by PRA, and although the clinical effects are usually the same, each breed's version of PRA is often caused by a different genetic mutation. Sadly there is no cure for PRA.

Clinical signs

Vision loss and eventual blindness.

How is it inherited?

The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories that test for BBs2-PRA can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
Laboratories Contact details
AHT (UK) The AHT closed down on 31 July and no longer offers this test.
Web:
www.aht.org.uk

Where will your dog's results be published?

DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:

How we record your results

Tested dogs will be recorded on The Kennel Club's systems as either:

Clear

The dog does not have any copies of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected and will only pass on a normal copy of the gene to a puppy.

Carrier

The dog has one copy of the normal gene and one copy of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected, but may pass one copy of the normal gene, or one copy of the abnormal gene on to a puppy.

Affected

The dog has two copies of the abnormal gene associated with the disease. The dog will likely be clinically affected by the disorder and will pass one copy of the abnormal gene on to any potential offspring.

How to responsibly breed from your DNA-tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on our Breed Register.