Details about the disease
AMPN causes reduced stimulation of the peripheral nervous system, which is followed by nerve degeneration. This then leads to gradual muscle deterioration.
Clinical signs
Clinical signs usually occur during the first two years of a dog’s life and include exercise intolerance, inability to move all limbs and loss of reflexes. Dogs affected with the condition may fall down, have an abnormal gait or walk on the tops of its feet.
How is it inherited?
The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected.
Which laboratories test for this condition?
Two lists of laboratories that test for AMPN can be found below.
Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
| Laboratories | Contact details |
|---|---|
| Animal DNA Diagnostics (UK) | Phone: 01223 395577 Email: Animal DNA Diagnostics Web: www.animaldnadiagnostics.co.uk |
| Laboklin (UK) | Phone: 0161 282 3066 Email: Laboklin Veterinary Diagnostic Laboratory Web: www.laboklin.co.uk |
| Pet Genetics Lab (UK) | Phone: 01624 679 720 Email: Pet Genetics Lab Web: www.petgeneticslab.co.uk |
Where will your dog's results be published?
DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:
- in the next available Breed Records Supplement
- on our Health Test Results Finder
Laboratories that do not send a copy of your dog's results to The Kennel Club. You'll need to do this yourself.
| Laboratories | Contact details |
|---|---|
| Genomia (Czech Republic) | Email:
Genomia Genetic Laboratory
Web: www.genomia.cz |
| MyDogDNA (Finland) | Email:
My Dog DNA
Web: www.mydogdna.com |
| HealthGene (Canada) | Email:
Web: www.healthgene.com |
| Paw Print Genetics (USA) | Email:
Paw Print Genetics
Web: www.pawprintgenetics.com |
| Van Haeringen (Holland) | Email:
Van Haeringen Genetics
Web: www.vhlgenetics.com |
| University of California (USA) | Web: www.vgl.ucdavis.edu |
How to submit DNA test results to The Kennel Club
The laboratories listed above do not send your dog's DNA test results to The Kennel Club. To have these results placed on your dog's record please submit them yourself by scanning and emailing them to our health results team.
What we require on the results certificate
Please note that we require at least two forms of identification on the result certificate. These must include the dog's microchip or tattoo number along with either the dog's registered name or registered number. Results without these details cannot be accepted by us.
Where will your dog's results be published once you have submitted them?
DNA test results received by The Kennel Club are added to the dog's record in the registration database, and are published:
- in the next available Breed Records Supplement
- on our Health Test Results Finder
Breeding advice and what your dog's results mean
If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.
How to find out if a potential mate has been DNA tested
The Kennel Club’s on our Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.