Irish Red & White Setter DNA screening

Distinguishing between clear, carrier and affected dogs

Clear dogs have no copies of the mutant gene responsible for the condition and will neither develop the condition nor pass the gene on to their offspring.

Carrier dogs have one copy of the normal gene and one copy of the mutant gene; they will not develop the condition, but will pass a mutant gene on to approximately half of their offspring.

Affected dogs have two copies of the mutant gene that causes the condition and will develop the disease.

Canine Leucocyte Adhesion Deficiency (CLAD)

The following breeding control scheme has been agreed by representatives of the Irish Red & White Setter Breed Clubs and the Kennel Club:

  • From 17th June 2003 all Irish Red & White Setters used for breeding should be either hereditarily clear of CLAD or have a CLAD DNA test before they are used for breeding.
  • Identified carriers can be used for breeding, but they should only be mated to a dog that is either hereditarily clear of CLAD or one that has DNA tested clear of CLAD; carriers should not be mated to carriers.
  • All of the registered offspring of a carrier mated to a clear should be clearly identified, DNA tested and registered as either tested clear or carrier.
  • From 17th June 2008 the Kennel Club will refuse registration of Irish Red & White Setter puppies unless both parents have been tested clear of CLAD, or are hereditarily clear of CLAD.
  • No carriers will be registered after 16th June 2008



von Willebrand's Disease (vWD)



Related Topics

Dna Screening Schemes DNA Screening
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