DNA test - vWD type I (von Willebrand disease)

Details about the disease

The condition is caused by a quantitative or qualitative deficiency of von Willebrand factor (vWF), a protein that plays a central role in blood clotting. Von Willebrand's disease vWD usually comes in three types, type I, type II and type III. Type III is a severe bleeding disorder with a high risk of spontaneous bleeding as well as a risk of serious bleeding from trauma and surgery. Type I is a less severe form.

Clinical signs

Dogs with vWD are prone to nose bleeds, bleeding from the gums, and prolonged bleeding during heat or after whelping. There may be prolonged bleeding from the umbilical cord at birth or when the pup sheds its baby teeth. Excessive bleeding after surgery or trauma is common, and may be the first sign of this condition in your dog. You may see blood in your dog's urine or stool. The clinical effects reported can range dramatically, with some dogs bleeding profusely, while others hardly showing any signs of bleeding at all.

How is it inherited?

The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

Two lists of laboratories that test for vWD can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
Laboratories Contact details
Animal DNA Diagnostics (UK) Phone: 01223 395577
Email: Animal DNA Diagnostics
Web: www.animaldnadiagnostics.co.uk
Animal Genetics (UK) Phone: 01726 247788
Email: Animal Genetics
Web: www.animalgenetics.eu
Laboklin (UK) Phone: 0161 282 3066
Email: Laboklin
Web: www.laboklin.co.uk
Pet Genetics Lab (UK) Phone: 01624 679 720
Email: Pet Genetics Lab
Web: www.petgeneticslab.co.uk 

Where will your dog's results be published?

DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:

Laboratories that do not send a copy of your dog's results to The Kennel Club. You'll need to do this yourself.
Laboratories Contact details
Antagene (France)
Not available for the Papillon.
Email Antagene
Web: www.antagene.com/en
DDC Veterinary (USA)
Only available for the following breeds:
  • Dobermann
  • Manchester Terrier
  • Poodle (Standard)
Email DDC Veterinary
Web: www.vetdnacenter.com
Genetic Technologies (Australia)
Only available for the following breeds:
  • Dobermann
  • Manchester Terrier
Web: www.animalnetwork.com.au

Genomia (Czech Republic)
Available for the Papillon only.

Email Genomia 
Web: www.genomia.cz


MyDogDNA (Finland)
Only available for the following breeds:
  • Dobermann
  • Manchester Terrier
  • Papillon
Email MyDogDNA
Web: www.mydogdna.com
Paw Print Genetics (USA) Email Paw Print Genetics
Web: www.pawprintgenetics.com

Pet Genetics Lab (UK)

Email Pet Genetics Lab

Web: www.petgeneticslab.co.uk  

 

Pinmoore Animal Lab Services (UK)
Only available for the following breeds:
  • Dobermann
  • Manchester Terrier
  • Poodle (Standard)
Phone: 01829 781855
Email Pinmoore Animal Lab Services
Web: www.palsvetlab.co.uk
Van Haeringen (Holland)
Only available for the following breeds:
  • Dobermann
  • Manchester Terrier
  • Poodle (Standard)
Email Van Haeringen
Web: www.vhlgenetics.com
VetGen (USA)

Web: www.vetgen.com

How to submit DNA test results to The Kennel Club

The laboratories listed above do not send your dog's DNA test results to The Kennel Club. To have these results placed on your dog's record please submit them yourself by scanning and emailing them to our health results team.

What we require on the results certificate

Please note that we require at least two forms of identification on the result certificate. These must include the dog's microchip or tattoo number along with either the dog's registered name or registered number. Results without these details cannot be accepted by us.

Where will your dog's results be published once you have submitted them?

DNA test results received by The Kennel Club are recorded on to the dog's record in the registration database, and are published:

How to responsibly breed from your DNA-tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.