DNA test Raine’s synd (Dental hypomineralisation/Raine’s syndrome)

Details about the disease

Dogs that are affected by dental hypomineralisation, otherwise known as Raine’s syndrome (or Raine’s synd. for short) have teeth that are not as strong as they should be. This means that their teeth can be worn down more easily and can cause the affected dog pain.

Clinical signs

Raine’s syndrome is known to affect Border Collies, with signs usually appearing at an early age. Affected dogs may develop brown discoloured teeth, smooth enamel, signs of wear, cracked teeth and inflammation. The only way to treat this condition is by extracting worn teeth.

How is it inherited?

The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected.

Which laboratories test for this condition?

A list of laboratories that test for Raine's syndrome can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.

Laboratories	Contact details
Animal Genetics (UK)	Phone: 01726247788 Email: Animal Genetics Web:www.animalgenetics.eu
Laboklin (UK)	Phone: 0161 282 3066 Email: Laboklin Veterinary Diagnostic Laboratory Web: www.laboklin.co.uk
Pet Genetics Lab	Email: Pet Genetics Lab Web: www.petgeneticslab.co.uk

Where will your dog's results be published?

DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:

in the next available Breed Records Supplement
on our Health Test Results Finder

How we record your results and what they mean

Tested dogs will be recorded on The Kennel Club's systems as either:

Clear

The dog does not have any copies of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected and will only pass on a normal copy of the gene to a puppy.

Carrier

The dog has one copy of the normal gene and one copy of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected, but may pass one copy of the normal gene, or one copy of the abnormal gene on to a puppy.

Affected

The dog has two copies of the abnormal gene associated with the disease. The dog will likely be clinically affected by the disorder and will pass one copy of the abnormal gene on to any potential offspring.

Breeding advice

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s on our Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.