DNA test - POAG (Primary open angel glaucoma)

Details about the disease

POAG is caused by a small increase in the fluid pressure within the eye and gradually results in blindness.

Clinical signs

The disease is normally seen in dogs aged between 3 and 6 years of age, but a later onset is also possible. Both eyes are affected, usually simultaneously and often the first indication of the presence of the disease is impaired vision or enlargement of the eye. However a close examination of the eye in early disease may reveal congestion of blood vessels in the normally white part of the eye, wobbliness of the lens and a reduced response of the pupil to bright light. It is a subtle disease and pain or discomfort is not a normal feature: measurement of the fluid pressure within the eye is the essential part of any professional examination.

How is it inherited?

The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories that test for POAG can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
Laboratories Contact details
AHT (UK) The AHT closed down on 31 July and no longer offers this test.
Web:
www.aht.org.uk

Where will your dogs results be published?

DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:

How to responsibly breed from your DNA-tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.