Details about the disease
POAG is caused by a small increase in the fluid pressure within the eye and gradually results in blindness. There are multiple mutations that have been associated with the clinical symptoms of POAG. POAG-4 is a mutation currently thought to be uniquely found in the Basset Fauve de Bretagne.
The disease is normally seen in dogs aged between 3 and 6 years of age, but a later onset is also possible. Both eyes are affected, usually simultaneously and often the first indication of the presence of the disease is impaired vision or enlargement of the eye. However a close examination of the eye in early disease may reveal congestion of blood vessels in the normally white part of the eye, wobbliness of the lens and a reduced response of the pupil to bright light. It is a subtle disease and pain or discomfort is not a normal feature: measurement of the fluid pressure within the eye is the essential part of any professional examination.
Find out more about POAG.
How is it inherited?
The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.
Which laboratories we record and publish the results from?
To find out which laboratories The Kennel Club is able to record results from, and which laboratories will send results directly to The Kennel Club, please refer to our website.
Please be aware, The Kennel Club has a set of criteria that we request DNA testing laboratories to meet to enable us to record their results, helping to maintain and protect the integrity of results that appear on a dog’s record. We strongly advise that customers ensure their chosen laboratory is included on our list if they wish The Kennel Club to record and publish the results. Results from laboratories not included on this list will not be recorded.
Breeding advice and what your dog's results mean
If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.
How to find out if a potential mate has been DNA tested
The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.