Details about the disease
LPN2 is a neuromuscular disease that causes nerve loss. The condition progresses severely to the extent where the dog is unable to support its own weight.
Clinical signs
Onset of clinical signs of type 2 neuropathy are variable, ranging from less than 1 year of age to 11 years of age, and include slowly worsening exercise intolerance, gait abnormalities, degeneration of hind leg muscles. Noisy breathing, difficulties swallowing and a change in their bark may also occur.
How is it inherited?
This disease is unique to Leonbergers and is described as an autosomal-dominant condition. This means that a dog must inherit only one copy of an abnormal gene (from either its mother or its father) before its health is affected.
Which laboratories test for this condition?
Two lists of laboratories that test for LPN2 can be found below.
Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
| Laboratories | Contact details |
|---|---|
| Laboklin (UK) | Phone: 0161 282 3066 Email: Laboklin Web: www.laboklin.co.uk |
Where will your dog's results be published?
DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:
- in the next available Breed Records Supplement
- on our Health Test Results Finder
Laboratories that do not send a copy of your dog's results to The Kennel Club. You'll need to do this yourself.
| Laboratories | Contact details |
|---|---|
| University of Bern (Switzerland) | Web: www.unibe.ch/eng |
| University of Minnesota (USA) | Email: University of Minnesota Web: www.vdl.umn.edu/services-and-fees/index.htm |
How to submit DNA test results to The Kennel Club
The laboratories listed above do not send your dog's DNA test results to The Kennel Club. To have these results placed on your dog's record please submit them yourself by scanning and emailing them to our health results team.
What we require on the results certificate
Please note that we require at least two forms of identification on the result certificate. These must include the dog's microchip or tattoo number along with either the dog's registered name or registered number. Results without these details cannot be accepted by us.
Where will your dog's results be published once you have submitted them?
DNA test results received by The Kennel Club are recorded on to the dog's record in the registration database, and are published:
- in the next available Breed Records Supplement
- on our Health Test Results Finder
How to responsibly breed from your DNA-tested dog
If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.
How to find out if a potential mate has been DNA tested
The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.