DNA test - JE (Juvenile epilepsy)

Details about the disease

JE is an inherited neurological disease and may be characterised by seizures in young puppies.

Clinical signs

Clinical signs usually begin in puppies at 3 to 9 weeks of age and usually resolve by 8 to 13 weeks of age at the latest. Clinical signs may be as mild as slight shivering or wobbly gait, but puppies with most severe seizures also have other neurological signs such as spastic paralysis or inability to walk. It should be noted that the expression of the abnormal gene is very variable. Even if puppies inherit two abnormal genes may show no signs of the disease. Conversely even puppies with severe clinical signs once the signs have resolved live a normal lifespan.

How is it inherited?

The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

Two lists of laboratories that test for JE can be found below.

Laboratories that send a copy of your dog's results straight to The Kennel Club, so you don't have to.
Laboratories Contact details
Animal DNA Diagnostics Phone: 01223 395577
Email: Animal DNA Diagnostics 

Web: www.animaldnadiagnostics.co.uk
Laboklin (UK) Phone: 0161 282 3066
Email: Laboklin
Web: www.laboklin.co.uk
Pet Genetics Lab (UK) Phone: 01624 679 720
Email: Pet Genetics Lab
Web: www.petgeneticslab.co.uk  

Where will your dog's results be published?

DNA test results from these laboratories are sent directly to The Kennel Club and are recorded on to the dog's record in the registration database, and are published:

Laboratories that do not send a copy of your dog's results to The Kennel Club. You'll need to do this yourself.
Laboratories Contact details
MyDogDNA (Finland) Email: MyDogDNA
Web: www.mydogdna.com
Paw Print Genetics (USA) Email: Paw Print Genetics
Web: www.pawprintgenetics.com
University of Bern (Switzerland) Web:  www.unibe.ch/eng
Van Haeringen (Holland) Email: Van Haeringen
Web: www.vhlgenetics.com

How to submit DNA test results to The Kennel Club

The laboratories listed above do not send your dog's DNA test results to The Kennel Club. To have these results placed on your dog's record please submit them yourself by scanning and emailing them to our health results team.

What we require on the results certificate

Please note that we require at least two forms of identification on the result certificate. These must include the dog's microchip or tattoo number along with either the dog's registered name or registered number. Results without these details can not be accepted by us.

Where will your dog's results be published once you have submitted them?

DNA test results received by The Kennel Club are recorded on to the dog's record in the registration database, and are published:

How to responsibly breed from your DNA-tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.