DNA test - Glanzmann’s Thrombasthenia

Details about the disease

Glanzmann’s Thrombasthenia is an inherited condition that causes affected dogs to have problems with their blood-clotting ability.

Clinical signs

Dogs usually show signs before they are a year old, often by bleeding from the gums as their adult teeth come through. Warning signs can include

bruising easily
frequently bleeding from the nose
blood in their urine
their stools may be red with fresh blood or black and tarry from old blood

How is it inherited?

The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories that test for Glanzmann’s Thrombasthenia can be found below.

Laboratories that do not send a copy of your dog's results to The Kennel Club. You'll need to do this yourself.

Laboratories	Contact details
Auburn University (USA)	Email: Auburn University Web: www.auburn.edu
Paw Print Genetics (USA)	Email: Paw Print Genetics Web: www.pawprintgenetics.com
Van Haeringen (Holland)	Email: Van Haeringen Genetics Web: www.vhlgenetics.com
VetGen (USA)	Email: Vet Gen Web: www.pawprintgenetics.com

How to submit DNA test results to The Kennel Club

The laboratories listed above do not send your dog's DNA test results to The Kennel Club. To have these results placed on your dog's record please submit them yourself by scanning and emailing them to our health results team.

What we require on the results certificate

Please note that we require at least two forms of identification on the result certificate. These must include the dog's microchip or tattoo number along with either the dog's registered name or registered number. Results without these details cannot be accepted by us.

Where will your dog's results be published once you have submitted them?

DNA test results received by The Kennel Club are recorded on to the dog's record in the registration database, and are published:

in the next available Breed Records Supplement
on our Health Test Results Finder

How we record your results

Tested dogs will be recorded on The Kennel Club's systems as either:

Clear

The dog does not have any copies of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected and will only pass on a normal copy of the gene to a puppy.

Carrier

The dog has one copy of the normal gene and one copy of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected, but may pass one copy of the normal gene, or one copy of the abnormal gene on to a puppy.

Affected

The dog has two copies of the abnormal gene associated with the disease. The dog will likely be clinically affected by the disorder and will pass one copy of the abnormal gene on to any potential offspring.

How to responsibly breed from your DNA-tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on our Breed Register.