DNA test - ENM (Hereditary necrotising myelopathy)

Details about the disease

ENM is a recessive spinal degenerative disease whereby the white matter of the spinal cord degrades in the neck region, affecting the motor function of the muscles of the hind limbs.

Clinical signs

Hereditary necrotising myelopathy causes progressive spinal degeneration in affected dogs. Clinical signs begin with paralysis of the hind limbs, an inability to place their feet, scuffed toes, excessively worn nails, shuffling and loss of coordination before progressing to an inability to walk within a few weeks. Early signs can usually be seen between 3 to 12 months of age and unfortunately there is no cure, resulting in the death of the dog.

How is it inherited?

The disease is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories we record and publish the results from?

To find out which laboratories The Kennel Club is able to record results from, and which laboratories will send results directly to The Kennel Club, please refer to our website.

Please be aware, The Kennel Club has a set of criteria that we request DNA testing laboratories to meet to enable us to record their results, helping to maintain and protect the integrity of results that appear on a dog’s record. We strongly advise that customers ensure their chosen laboratory is included on our list if they wish The Kennel Club to record and publish the results. Results from laboratories not included on this list will not be recorded.

Breeding advice and what your dog's results mean

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and DNA testing information.

How to find out if a potential mate has been DNA tested

The Kennel Club’s Health Test Results Finder allows you to find the results of DNA tests carried out as part of The Kennel Club's official DNA testing schemes for any dog on The Kennel Club’s Breed Register.