Glossary

Screening Scheme Description

DNA test - IMGD
Inherited Myopathy of Great Danes

Details about the disease

IMGD or Inherited Myopathy of Great Danes is an inherited muscle disorder that gets worse with time. This particular condition only appears to affect Great Danes. Dogs typically begin to show signs around 6 months of age and many are euthanised before a year old, although a small number do stabilise and live to adulthood.

Clinical signs

Onset – 6 to 12 months. Signs include; difficulty exercising, tremors (particularly brought on by exercise), weakness, muscle wasting, abnormal posture or gait.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link www.thekennelclub.org.uk/health/for-breeders/dna-testing-simple-inherited-disorders/worldwide-dna-tests/

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link http://bit.ly/2oSbtnn.

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link http://bit.ly/1jyCFnc.

 


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