Screening Scheme Description

DNA test - HNPK
Hereditary Nasal Parakeratosis

Retriever (Labrador)

Details about the disease

Hereditary Nasal Parakeratosis causes the nose to dry out which leads to inflammation and continuous irritation of the skin on the nose.

Clinical signs

Clinical signs include the nose surface to be dry, rough and eventually show a change in skin colour from a dark to lighter colour. Brown crusts may also develop on the surface and edge of the nose. Affected dogs start showing these signs from 6-12 months of age.

How it is inherited

The disease is unique to the Labrador Retriever and is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link


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