Glossary

Screening Scheme Description

DNA test - prcd-PRA
Progressive rod cone degeneration - Progressive retinal atrophy

Details about the disease

The cells of the retina receive light from the external environment and transmit the information to the brain where it is interpreted to become vision. PRA causes cells in the retina at the back of the eye to degenerate and die, even though the cells may have developed normally early in life.

Clinical signs

Owners of affected dogs first notice that their dog becomes night blind, but this eventually progresses to total blindness. The age of onset of first signs varies from breed to breed, however, in all cases puppies are born with perfect vision and their sight begins to degenerate later in life, from around 3 years of age or later.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link http://www.thekennelclub.org.uk/health/for-breeders/dna-testing-simple-inherited-disorders/worldwide-dna-tests/

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link http://bit.ly/2oSbtnn.

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link http://bit.ly/1jyCFnc.

 

Copyright © The Kennel Club Limited 2017. The unauthorised reproduction of text and images is strictly prohibited.