Screening Scheme Description


In the Shar Pei, both POAG and PLL appear to be caused by the same mutation.

Details about the disease

Primary Glaucoma is a painful and blinding disease associated with high pressure inside the eye. In POAG/PLL, glaucoma results from reduced drainage of fluid from the eye, causing a build-up of pressure which then leads to pain and blindness

Clinical signs

Most dogs become affected at approximately 4-6 years of age. The eyes become enlarged and the lens of the eye becomes wobbly and can even fall out of its normal position.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

For advice on breeding for health, why not visit our information guide

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link


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