Glossary

Screening Scheme Description

DNA test - PCD
Primary Ciliary Syskinesia

Details about the disease

PCD is characterised by the interference of clearing mucus from the airways, causing chronic inflammation of the nasal cavities, windpipe and lower airways. It also causes regular infections, due to the obstruction of fluid moving through the airways. The disorder causes sperm immotility and affected dogs are sterile.

Clinical signs

Clinical signs of PCD include sneezing, nasal discharge, cough and chronic bronchitis, which is due to recurrent infection of the upper and lower respiratory tract. Effects also include hydrocephalus (increase of fluid around the brain) and reduced fertility in males.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link http://www.thekennelclub.org.uk/health/for-breeders/dna-testing-simple-inherited-disorders/worldwide-dna-tests/

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link http://bit.ly/2oSbtnn.

 

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