Glossary

Screening Scheme Description

DNA test - JLPP
Juvenile Laryngeal Paralysis & Polyneuropathy

Details about the disease

JLPP is a disease that causes deterioration of the nervous system. The longest nerve which controls the muscles of the larynx (voice box) is affected first. This leads to muscle weakness and obstruction of air flow into the lungs after exercise or when the dog is hot.

Clinical signs

Clinical signs include noisy breathing, choking and regurgitation of food and water. Signs also include a wobbly gait due to affected nerves that control the hind leg muscles. Other signs include eye development abnormalities. Clinical signs usually start at a few weeks of age.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link http://www.thekennelclub.org.uk/health/for-breeders/dna-testing-simple-inherited-disorders/worldwide-dna-tests/

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link http://bit.ly/2oSbtnn.

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link http://bit.ly/1jyCFnc.

 

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