Screening Scheme Description

DNA test - JE
Juvenile Epilepsy

Details about the disease

JE is an inherited neurological disease and may be characterised by seizures in young puppies.

Clinical signs

Clinic signs usually begin in puppies at 3 to 9 weeks of age and usually resolve by 8 to 13 weeks of age at the latest. Clinical signs may be as mild as slight shivering or wobbly gait, but puppies with most severe seizures also have other neurological signs such as spastic paralysis or inability to walk. It should be noted that the expression of the abnormal gene is very variable. Even if puppies inherit two abnormal genes may show no signs of the disease. Conversely even puppies with severe clinical signs once the signs have resolved live a normal lifespan.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

For advice on breeding for health, why not visit our information guide

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link


Copyright © The Kennel Club Limited 2020. The unauthorised reproduction of text and images is strictly prohibited.