Glossary

Screening Scheme Description

DNA test - ENM
Hereditary Necrotising Myelopathy

Details about the disease

ENM is a recessive spinal degenerative disease whereby the white matter of the spinal cord degrades in the neck region, affecting the motor function of the muscles of the hind limbs.

Clinical signs

Hereditary necrotising myelopathy causes progressive spinal degeneration in affected dogs. Clinical signs begin with paralysis of the hind limbs, an inability to place their feet, scuffed toes, excessively worn nails, shuffling and loss of coordination before progressing to an inability to walk within a few weeks. Early signs can usually be seen between 3 to 12 months of age and unfortunately there is no cure resulting in the death of the dog.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

For advice on breeding for health, why not visit our information guide www.thekennelclub.org.uk/media/451962/breeding_health.pdf

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link http://www.thekennelclub.org.uk/health/for-breeders/dna-testing-simple-inherited-disorders/worldwide-dna-tests/

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link http://bit.ly/2oSbtnn.

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link http://bit.ly/1jyCFnc.

 

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