Screening Scheme Description

DNA test - DE
Degenerative Encephalopathy

Details about the disease

Degenerative Encephalopathy is a neurological disorder and is characterised by degeneration of the part of the brain that is important for controlling movement and some aspects of behaviour.

Clinical signs

Clinical signs include loss of coordination (problems running, jumping or swimming), anxious and aggressive behaviour, excessive focus on food and abnormal tail position. These signs become gradually worse with age, with most affected dogs being euthanized by 3-5 years of age due to poor quality of life.

How it is inherited?

The disease described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link


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