Glossary

Screening Scheme Description

DNA test - AMS
Acral Mutilation Syndrome

Details about the disease

AMS is the self-mutilation of limb extremities linked with located insensitivity to pain

Clinical signs

Clinical signs include severe licking of footpads and paws to the point of bleeding, ulceration. Auto-amputation of the claws, footpads, and digits through self-mutilation can also occur. Lesions (wounds) on limbs and inability to feel pain on distal limbs are also clinical signs. Age of onset ranges from 3 to 12 months.

How it is inherited

The disease is described as an autosomal recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

For advice on breeding for health, why not visit our information guide www.thekennelclub.org.uk/media/451962/breeding_health.pdf

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link http://www.thekennelclub.org.uk/health/for-breeders/dna-testing-simple-inherited-disorders/worldwide-dna-tests/

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link http://bit.ly/2oSbtnn.

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link http://bit.ly/1jyCFnc.

 

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