Screening Scheme Description

DNA test - NCCD
Neonatal Cerebellar Cortical Degeneration


Details about the disease

The clinical signs of NCCD are due to damage in their cerebellum, which is the part of the brain that controls movement and balance. This disease has minimal progression, but currently has no cure.

Clinical signs

Affected puppies start showing clinical signs around 3 weeks of age. They are slower and less coordinated than unaffected puppies, falling more often and unable to walk in a correct manner. Signs include tremor, ataxia (inability to coordinate the movement of muscles) and spastic paralysis.

How it is inherited

The disease is described as a recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Which laboratories test for this condition?

A list of laboratories and DNA tests can be found at the following link

How to responsibly breed from your DNA tested dog

If, once your dog is DNA tested, you would like to find out what their DNA test results mean, or how to select the right mate to avoid producing affected puppies, then please read our breeding advice and information on the following link

How to find out if a potential mate has been DNA tested

The Kennel Club’s “Health Test Results Finder” allows you to find the results of DNA tests carried out as part of official Kennel Club DNA testing schemes for any dog on the Kennel Club’s breed register. To access this free health tool, please follow this link


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