The Kennel Club has approved a new health programme, in
collaboration with the Dalmatian breed clubs, which are
collectively supportive of a DNA test for the SLC2A9 gene
associated with Hyperuricosuria (HUU)/Urate Stone Disorder
Hyperuricosuria is an inherited condition which can affect
Dalmatians. Dogs with two copies of the SLC2A9 gene (one inherited
from their mother and one inherited from their father) are
predisposed to higher levels of uric acid in their urine.
These increased levels can lead to crystals and stone structures
forming in the urinary tract, which may cause infections, blood in
the urine and blockage of the urethra (the tube that takes urine
out of the body from the bladder).
This DNA test is particularly relevant to Dalmatian outcrosses and
subsequent generations of progeny derived from such
Acceptance of results for this test by the Kennel Club is
conditional upon the following test protocols:
- that dogs to be tested are microchipped and registered before
the test sample is taken;
- that the test sample (whether buccal swab or blood sample or
other) is taken by a veterinary surgeon or veterinary nurse who
first confirms the microchip identity of the test subject and
records both the microchip number and registration name on the
- that the sample is sent directly by the veterinary
surgery to the testing laboratory; and
- that the testing laboratory is one which is approved by, or
acceptable to, the Kennel Club.
Copies of all future test certificate results issued by the
following laboratories will be recorded at this time, provided they
comply with the above protocols:
- Animal Health Trust
- Animal DNA Diagnostics
- Animal Genetics
Caroline Kisko, Kennel Club Secretary, said: "The Kennel Club is
constantly reviewing health programmes and testing schemes in
conjunction with breed clubs to ensure that the tools are in place
for breeders to be able to continue breeding healthy dogs.
"We are pleased to be announcing this new health programme for
Dalmatians, which will help breeders make informed decisions when
it comes to breeding, enable potential puppy buyers to be aware of
issues which could affect their breed, and ultimately further
protect and maintain the health of Dalmatians.
"The Kennel Club continues to work alongside breed clubs and breed
health coordinators, in a collaborative effort to improve the
health of pedigree dogs. We are happy to accommodate a club's
request to add a new DNA test to its lists and would normally need
a formal request from the breed's health coordinator or a majority
request from the breed clubs."
Test results will be added to the dog's registration details which
will trigger the publication of the result in the next available
Breed Records Supplement. The result will appear on any new
registration certificate issued for the dog and on the registration
certificates of any future progeny of the dog, and also on the
Health Test Results Finder on the Kennel Club website.
If the owner includes the original registration certificate for
the dog (not a copy) then a new registration certificate will be
issued, with the DNA result on it, free of charge. Please send any
DNA test certificates to Health & Breeder Services, The Kennel
Club, Clarges Street, London, W1J 8AB or scan and email copies of
the certificates to firstname.lastname@example.org.