DNA Screening - PRA Irish Setter
Important information about the DNA Test Control Scheme – GPRA rcd-1
As of 1st January 2010, the Kennel Club will only register Irish Setters that are proven clear of the GPRA rcd-1 mutation, either by direct DNA testing or by virtue of having parents that are proven to be clear of the GPRA rcd-1 mutation (i.e. hereditarily clear).
The following Irish Setters have been DNA tested for progressive retinal atrophy (GPRA rcd-1). The test distinguishes between clear, carrier and affected dogs. Clear dogs have no copies of the mutant gene responsible for GPRA and will neither develop the condition nor pass a GPRA gene on to their offspring. Carrier dogs have one copy of the normal gene and one copy of the mutant gene; they will not develop the condition, but will pass a mutant gene on to approximately half of their offspring. Affected dogs have two copies of the mutant gene that causes GPRA and will develop the disease.
The results presented in black type below are from tests carried out by The Animal Health Trust; results presented in blue type face are from tests performed at the Veterinary School, Cambridge University.
A tables listing Clears (in PDF format) is available from the following link:
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